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Alzheimer Disease and Nonfluent Progressive Aphasia Arch Neurol 53:1072-1078, Greene,J.D.W.,et al, 1996 See this aricle in Pubmed Article Abstract Neuropsychological testing revealed mild global intellectual impairment with marked impairment of auditory verbal short-term memory,syntactic,and phonological abilities.His naming errors were predominantly phonological paraphasias.Magnetic resonance imaging scans showed left perisylvian atrophy and results of a Tc 99m hexamethyl-propyleneamine-oxime single photon emission computed tomographic scan were normal.Postmortem pathological examination revealed typical AD pathological features with atypical distribution,involving predominantly perisylvian language areas, but sparing the medial temporal lobe.The language deficits in AD,which have received considerable attention are thought to involve predominantly lexicosemantic processes.When AD presents as a relatively isolated language disturbance,the aphasia is usually of the fluent anomic type.To our knowledge,our patient represents the first fully documented case of progressive nonfluent aphasia with pathologically verified AD

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(click to filter results - removes previous filter) Alzheimer's disease aphasia aphasia,progressive aphasia,progressive,primary seizure Wernicke's aphasia

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